The Bowtie 2 software achieves fast, sensitive, accurate and memory-efficient gapped alignment of sequencing reads using the full-text minute index and hardware-accelerated dynamic programming ...

The informatics revolution in both bioinformatics and clinical informatics will eventually change the current practice of medicine, including diagnostics, therapeutics, and prognostics.

Bioinformatics workflows The declining cost and increasing accessibility of next-generation sequencing (NGS) have led to the permeation of these techniques throughout the life sciences. The sequencing ...

The Genomics & Bioinformatics shared resource helped the Hutch’s Henikoff Lab develop a better chromatin mapping technique.

While the normal practice is to use various alignment techniques like BLAST, CLUSTALW, etc. to measure such differences, our approach allows for a novel method of genome characterization called ...