Which of the many methods to isolate RNA is best suited for microarray analyses, especially on large numbers of clinical studies, warrants future study.

Assay development and validation We developed a method to achieve high-throughput gene expression analyses of miRNAs. We sought to eliminate systematic bias associated with RNA ligation steps ...

An article published in the journal BMC Genomics details how researchers have optimized a miniaturized cell spot microarray method to facilitate reproducible preparation of highly parallel cell ...

Because microarray assays can analyze the expression of multiple genes in parallel, they have been proposed as a robust test method for diagnostic usage in a clinical laboratory. However, published ...

In short, protein microarray technology provided a diagnostic method with at least one hundred times the sensitivity than standard diagnostic methods, along with lower sample volume requirements.

This review outlines protein microarray techniques that are currently being used for analytical and function-based proteomics, providing a detailed analysis of recent advances in this technology.

Abstract Self-assembling protein microarrays arrays can be used to study protein-protein interactions, protein-drug interactions, search for enzyme substrates, and as tools to search for disease ...

The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses. The phase 1/2 randomized trial compared results ...

Given the increasing evidence of importance of the microenvironment for tumor invasion, progression and metastasis, we explored tumor stroma gene signature using microarrays. Methods: Four ...

Protein microarrays are one aspect of highly automated, large-scale biological screening technologies, the other is nucleic acid arrays.

A dual fluorescence method has been used for the detection of biomarkers in prostate cancer; serum samples from 33 patients and 20 healthy controls analyzed on a microarray immobilized with 180 ...