The findings were independently validated using multiple approaches for whole mitochondrial DNA sequencing. The pattern of paternal inheritance of mitochondrial DNA appears to be determined in an ...

As such, inheritance of mitochondrial respiratory chain disease can either follow dominant or recessive autosomal (Mendelian) inheritance patterns, the strictly matrilineal inheritance observed ...

If the pattern of inheritance is identical, this evidence stable maternal inheritance of the mitochondrial DNA. In humans there is no genetic material that is only transferred through females.

Seven strains of the Central American A1 mating series of Didymium iridis were crossed in all possible combinations. Individual plasmodia were isolated and grown to a stage where total DNA could be ...

In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...

However, paternal mtDNA inheritance may go unrecognized in cases with sporadic, single, large-scale deletions, because mitochondrial haplotypes are rarely investigated in diagnostic analyses.

The vast majority of our DNA—the chromosomes in the nucleus of each cell—is just what you’d expect: a mix of genetic material from both mother and father. But mitochondria are an exception. They ...

In September 6 Nature, Sofia Berlin and Hans Ellegren from Uppsala University, Sweden, examine the controversial clonal inheritance theory for vertebrate mitochondrial DNA (mtDNA) by following ...

Biochemical and DNA analysis suggested an isolated deficiency of the mitochondrial enzyme complex 1 of the respiratory chain in muscle, caused by a novel 2-bp mtDNA deletion in the ND2 gene.

Hagelberg believes that mitochondrial DNA inheritance is more complicated than many people would suggest. "When you analyze the DNA sequences, it is clear that inheritance is not straightforward ...