Alignment of DNA and protein sequences is a basic tool in the study of evolutionary, structural and functional relationship among macromolecules. Present sequence alignment methods are somewhat ...

Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.

Aligning multiple nucleotide sequences is a prerequisite for many if not most comparative sequence analyses in evolutionary biology. These alignments are often recognized as representing the homology ...

Christopher J. Fallaize, Peter J. Green, Kanti V. Mardia, Stuart Barber, Bayesian protein sequence and structure alignment, Journal of the Royal Statistical Society ...

BLAST (Basic Local Alignment Search Tool): Helps identify homologous sequences by comparing a query sequence to a database. Clustal Omega: Performs multiple sequence alignments, essential for ...

Edgar calls his new algorithm MUSCLE (multiple sequence comparison by log expectation). MUSCLE uses a log expectation score to control progressive alignment of the input amino acid sequences. This ...