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生物通
11 天
EGFR-TKIs耐药后分子检测与治疗策略优化:中国非小细胞肺癌真实世界 ...
来自中国16家中心的研究团队针对EGFR-TKIs一线治疗进展后的非小细胞肺癌 (NSCLC)患者,开展多中心前瞻性研究 (PISCES),揭示分子检测率仅73.2%,T790M突变阳性患者接受三代EGFR-TKIs二线治疗可获得14.7个月mPFS和32.0个月mOS,为精准治疗决策提供重要循证依据。 当第一代 (1 G )/第二代 (2 G )EGFR酪氨酸激酶抑制剂 ...
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